| 致力于黑曲霉系统与合成生物学研究，重点开发系统生物学技术与黑曲霉基因组编辑技术，整合多组学数据，解析黑曲霉独特的分子机制，辅以计算机设计开发创建新型丝状真菌细胞工厂，实现工业化菌株的个性化定制。在ACS Synth Biol、Biotechnol J、Microb Cell Fact与Biotechnol Biofuels等杂志上发表SCI论文十余篇，申请中国发明专利1项。代表论著：
1） Zheng X, Zheng P, Zhang K, Cairns TC, Meyer V, Sun J, Ma Y. 5S rRNA Promoter for Guide RNA Expression Enabled Highly Efficient CRISPR/Cas9 Genome Editing in Aspergillus niger. ACS Synth Biol. 2018 Apr 30.
2） Zheng X, Zheng P, Sun J, Zhang K, Ma Y. Heterologous and endogenous U6 snRNA promoters enable CRISPR/Cas9 mediated genome editing in Aspergillus niger. Fungal Biol Biotechnol. 2018 Feb 8;5:2.
3） Zheng X, Yu J, Cairns TC, Zhang L, Zhang Z, Zhang Q, Zheng P, Sun J, Ma Y. Comprehensive Improvement of Sample Preparation Methodologies Facilitates Dynamic Metabolomics of Aspergillus niger. Biotechnol J. 2019 Mar;14(3):e1800315.
4） Tong Z#, Zheng X#, Tong Y, Shi YC, Sun J. Systems metabolic engineering for citric acid production by Aspergillus niger in the post-genomic era. Microb Cell Fact. 2019 Feb 4;18(1):28.
5） Zhang Q#, Zheng X#, Wang Y, Yu J, Zhang Z, Dele-Osibanjo T, Zheng P, Sun J, Jia S, Ma Y. Comprehensive optimization of the metabolomic methodology for metabolite profiling of Corynebacterium glutamicum. Appl Microbiol Biotechnol. 2018 Jun 6.
6） Cairns TC, Zheng X, Zheng P, Sun J, Meyer V. Moulding the mould: understanding and reprogramming filamentous fungal growth and morphogenesis for next generation cell factories. Biotechnol Biofuels. 2019 Apr 2;12:77.
7） Cairns TC#, Feurstein C#, Zheng X, Zheng P, Sun J, Meyer V. A quantitative image analysis pipeline for the characterization of filamentous fungal morphologies as a tool to uncover targets for morphology engineering: a case study using aplD in Aspergillus niger. Biotechnol Biofuels. 2019 Jun 15;12:149.
8） Wang X, Li Q, Sun C, Cai Z, Zheng X, Guo X, Ni X, Zhou W, Guo Y, Zheng P, Chen N, Sun J, Li Y, Ma Y. GREACE-assisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli. Microb Cell Fact. 2019 Jun 11;18(1):106.
9） Wang Y, Liu Y, Liu J, Guo Y, Fan L, Ni X, Zheng X, Wang M, Zheng P, Sun J, Ma Y. MACBETH: Multiplex automated Corynebacterium glutamicum base editing method. Metab Eng. 2018 May; 47:200-210.
10）Wanka F, Cairns T, Boecker S, Berens C, Happel A, Zheng X, Sun J, Krappmann S, Meyer V. Tet-on, or Tet-off, that is the question: Advanced conditional gene expression in Aspergillus. Fungal Genet Biol. 2016 Apr;89:72-83.
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